A RANDOMIZED CONTROL TRIAL TO EVALUATE THE EFFECT OF LOCAL INSTILLATION OF MITOMYCIN-C AT THE PORTA AFTER KASAI PORTOENTEROSTOMY IN PATIENTS OF BILIARY ATRESIA

A randomized control trial to evaluate the effect of local instillation of mitomycin-C at the porta after kasai portoenterostomy in patients of biliary atresia

Background: Kasai portoenterostomy (KPE) Cutting Saddles is the initial treatment for biliary atresia (BA).Even after initial jaundice clearance, a significant number of children presented with the reappearance of symptoms due to ongoing fibrosis involving porta and intrahepatic ducts.Mitomycin-C (MMC) is an antifibrotic agent, and the study hypoth

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Evaluation of the effectiveness of introducing new alleles into the gene pool of a rare dog breed: Polish Hound as the example

The objective of the analysis was to check the possibility of enriching a gene pool of a rare dog breed by breeding use of dogs of unknown origin that are phenotypically similar to a given breed.The evaluation was performed using pedigree and mtDNA analyses applied to Polish Hounds.The results indicated the very limited breeding success of such dog

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